Generic:

Furosemide

Brand:

Lazicare

Dosage Form and Strength:

10 mg/mL (20 mg/2 mL) Solution for Injection (I.M./I.V.)

Availability:

Brown Low Borosilicate Glass (2 mL) (Box of 10s)

Each mL contains:

10 mg Furosemide

Dosage and Administration:

Furosemide may be administered intramuscularly or intravenously as the sodium salt. It is recommended that whether by direct intravenous injection or by infusion, the rate of intravenous administration should not exceed 4 mg/minute although some authorities advise that a single dose of up to 50 mg may have given more rapidly.

Edema:

20-50 mg of Furosemide may be administered by intramuscular or slow intravenous injection and if necessary further doses may be given, increasing by 20 mg increments and not given more often than every 2 hours. If doses are greater than 50 mg are required they should be given by slow intravenous infusion. For pulmonary edema, if an initial slow intravenous injection of 40 mg dose does not produce a satisfactory response within 1 hour, the dose may be increased to 80 mg given slowly intravenously.

Children:

0.5 to 1.5 mg per kg daily up to a maximum of 20 mg daily.

High dose therapy:

250 mg diluted to 250 mL in a suitable diluent is infused over 1 hour. If urine output is sufficient within the next hour this dose may be followed by 500 mg added to an appropriate infusion fluid, the total volume which must be governed by the patient’s state of hydration and infused over approximately 2 hours.or as prescribed by a physician.

Indication:

Furosemide is a potent diuretic with a rapid action. Like the other loop or high ceiling diuretics, it is used in the treatment of edema associated with heart failure, including pulmonary edema and with renal and hepatic disorders and may be effective in patients unresponsive to thiazide diuretics. It is also used in high doses in the management of oliguria due to renal failure or insufficiency. It is also used in the treatment of hypertension either alone or together with other antihypertensives.

Contraindication:

Although Furosemide is used in high doses for oliguria due to chronic or acute renal insufficiency it should not be given in anuria or in renal failure caused by nephrotoxic or hepatotoxic drugs nor in renal failure associated with hepatic coma. It should not be given in pre-comatose states associated with hepatic cirrhosis.

Precaution:

Furosemide should be used with caution in patients with existing fluid and electrolyte disturbances or who are at risk from changes in fluid and electrolyte balance, such as the elderly. They should be avoided in patients with hepatic impairment, in whom encephalopathy may be precipitated. It should be used with care in patients with prostatic hyperplasia or impairment of micturition since it can precipitate acute urinary retention.

Storage Condition:

Store at temperature not exceeding 30°C.

Imported and Distributed by:

EURO-CARE PRODUCTS, PHILS.

Tinio St., San Nicolas
Gapan City, Nueva Ecija

Manufactured by:

FUREN PHARMACEUTICAL GROUP CO., LTD.

Henan, China